Xingjuan Shi
Associate Professor, Ph.D. Supervisor
E-mail: xingjuanshi@seu.edu.cn
Office：B405 Huichuan Building, Jiangbei Campus, Southeast University
Education & Research experience
2003 - 2007 Bachelor, Bioengineering, Southwest Jiaotong University
2007 - 2012 Ph.D., Cell Biology, Nankai University
2014 - 2016 Visiting scientist, University of Toronto
2012 - 2018 Instructor, School of Life Science and Technology, Southeast University
2018 - present Associate Professor, School of Life Science and Technology, Southeast University
Research interests
1. The molecular mechanisms underlying cardiomyopathy
2. Cellular homeostasis and metabolic fatty liver disease
Representative publications (*co-first author; #corresponding author)
1. Yao J, Zhao Z, Chen Y, Xu X, Yang Y, Yue W, Shi X*. Histone deacetylase 6 deacetylates and ubiquitinates ATG3 to regulate autophagy. Cell Death & Differentiation. 2026 Jan;33(1):188-199.
2. Yao J, Sun X, Chen Y, Xu X, Feng J, Zhang M, Liu X, Shi X*. Histone deacetylase 6 inhibition attenuates pathological cardiac hypertrophy by promoting autophagy through MAP1LC3B ubiquitination. Journal of Pathology. 2025 Jun;266(2):217-229.
3. Shi X*, Yao J, Huang Y, Wang Y, Jiang X, Wang Z, Zhang M, Zhang Y, Liu X. Hhatl ameliorates endoplasmic reticulum stress through autophagy by associating with LC3. Journal of Biological Chemistry. 2024 Jun;300(6):107335.
4. Shi X*, Jiang X, Chen C, Zhang Y, Sun X*. The interconnections between the microtubules and mitochondrial networks in cardiocerebrovascular diseases: Implications for therapy. Pharmacological Research. 2022 Oct;184:106452.
5. Zhang H, Liu B, Shi X*, Sun X*. Long noncoding RNAs: Potential therapeutic targets in cardiocerebrovascular diseases. Pharmacology & Therapeutics. 2020 Nov 10:107744.
6. Shi X*, Li D, Wang Y, Liu S, Qin J, Wang J, Ran J, Zhang Y, Huang Q, Liu X, Zhou J, Liu M. Discovery of Centrosomal Protein 70 as an Important Player in the Development and Progression of Breast Cancer. American Journal of Pathology. 2017 Mar;187(3):679-688.
7. Qiu F#, Tang R#, Zuo X#, Shi X#, Wei Y#, Zheng X#, Dai Y, Gong Y, Wang L, Xu P, Zhu X, Wu J, Han C, Gao Y, Zhang K, Jiang Y, Zhou J, Shao Y, Hu Z, Tian Y, Zhang H, Dai N, Liu L, Wu X, Zhao W, Zhang X, Zang Z, Nie J, Sun W, Zhao Y, Mao Y, Jiang P, Ji H, Dong Q, Li J, Li Z, Bai X, Li L, Lin M, Dong M, Li J, Zhu P, Wang C, Zhang Y, Jiang P, Wang Y, Jawed R, Xu J, Zhang Y, Wang Q, Yang Y, Yang F, Lian M, Jiang X, Xiao X, Li Y, Fang J, Qiu D, Zhu Z, Qiu H, Zhang J, Tian W, Chen S, Jiang L, Ji B, Li P, Chen G, Wu T, Sun Y, Yu J, Tang H, He M, Xia M, Pei H, Huang L, Qing Z, Wu J, Huang Q, Han J, Xie W, Sun Z, Guo J, He G, Eric Gershwin M, Lian Z, Liu X, Seldin MF, Liu X*, Chen W*, Ma X*. A genome-wide association study identifies six novel risk loci for primary biliary cholangitis. Nature Communications. 2017 Apr 20;8:14828.